Invited review: A critical appraisal of mastitis vaccines for dairy cows
نویسندگان
چکیده
Infections of the mammary gland remain a frequent disease dairy ruminants that negatively affect animal welfare, milk quality, farmer serenity, and farming profitability cause an increase in use antimicrobials. There is need for efficacious vaccines to alleviate burden mastitis farming, but this has not been satisfactorily fulfilled despite decades research. A careful appraisal past current research on reveals peculiarities also commonalities among infections associated with major pathogens Escherichia coli, Staphylococcus aureus, Streptococcus uberis, agalactiae, or dysgalactiae. pitfall immune mechanisms effective protection have fully identified. Until now, vaccine development directed toward generation antibodies. In review, we drew up inventory main approaches used design aim at gland, critically appraised tentative vaccines. particular, sought relate efficacy vaccine-induced defense shed light some possible reasons shortcomings. Based lessons learned from attempts recent results research, may take new turn years come.
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ژورنال
عنوان ژورنال: Journal of Dairy Science
سال: 2021
ISSN: ['0022-0302', '1525-3198', '1529-9066']
DOI: https://doi.org/10.3168/jds.2021-20434